DDL2024 Programme

08:00

Registration and Refreshments

10:15 - 10:30

Conference Opens

Welcome by Gary Pitcairn, DDL Conference Chair

10:30 - 10:35

SESSION 1 – TRANSITION TO NEW PROPELLANTS – CURRENT SOLUTION AND FUTURE THREAT

This panel discussion will focus on the formulation of inhaled medicines using new low global warming propellants to replace existing propellants in MDIs and lessons learned, opportunities, and challenges.
The panel, consisting of representatives from consortia and industry, will provide an update and their views on the evolving regulatory and policy framework, reflect on the implications of both F-gas regulation and PFAS debate on this transition taking into account the role of industry, clinicians and the voice of the patient.
The talks will be followed by a panel discussion including the audience.

10:35 - 10:50

Maureen Hardwick, International Pharmaceutical Aerosol Consortium (IPAC)

10:50 - 11:05

Sara Panigone, Chiesi Group

11:05 - 11:20

John Bell, AstraZeneca

11:20 - 11:50

Panel Discussion – all speakers

11:50 - 12:50

Networking Lunch in the Exhibition Hall and Poster Hall

Network with delegates and view the industry exhibition.

Visit the conference posters exhibition on Level 0.

Lunch is served in the exhibition hall and the poster hall.

11:50 - 12:50

The DDL New Researcher Networking Lunch

Lunchtime Networking Game Session – for new and early career scientists and PhD students only.

Lowther Meeting Room, Level -1

Full information and booking here

The DDL Annual Lecture

The DDL Lecture is a prestigious accolade bestowed on individuals who have contributed much to the field of respiratory science.

Awarded to:

12:55 - 13:25

Delivering Aerosols to Premature Infants, a Most Challenging and Precious Patient: Accelerating Development using Realistic Airway Models

Mike Hindle, Virginia Commonwealth University

 

13:25 - 13:30

SESSION 2 – INHALATION ACROSS THE AGES

13:30 - 13:55

Challenges of aging

Dermot Ryan, University of Edinburgh

13:55 - 14:10

In vitro – in vivo correlation of levodopa dry powder for inhalation

Julia Berends, University of Groningen

14:10 - 14:35

Challenges and opportunities for improving inhaler adherence – its child’s play!

Louise Fleming, Imperial College Healthcare trust and Royal Brompton Hospital

14:35 - 14:50

Asthma monitoring in paediatric asthmatic patients with the mannitol challenge test

Sharon Shui Yee Leung, Chinese University of Hong Kong

14:50 - 16:25

Refreshment Break 

Explore the exhibition stands and network with delegates

Manned Poster Session – speak to the conference poster authors in this manned poster session.

The poster exhibition is on Level 0.

Poster presenters will be interviewed by the DDL Judges to be considered for the Best Academic and Best Industry Poster at DDL2024.

16:25 - 16:30

SESSION 3 – GENE THERAPY AND BIOLOGICS FOR THE LUNGS

16:30 - 16:55

Gene therapy for cystic fibrosis – the challenges

Eric Alton, Imperial College London

16:55 - 17:10

Modelling Proteins in Amorphous Solid Dispersed Formulations for Inhaled Biologics

Emilie Gerrard, AstraZeneca

17:10 - 17:25

Enhancing the intranasal delivery of mRNA therapeutics using a novel thermosensitive polymer

Hui Xin (YY) Ong, Ab Initio Pharma

17:25 - 17:50

Advancements in Inhaled RNA Therapeutics: Overcoming Challenges from an Industrial Perspective

Kristina Pagh Friis, AstraZeneca

17:50 - 20:00

Welcome Drinks Reception

Networking across the conference centre, with drinks, snacks and entertainment in the exhibition hall and the poster hall.

17:50 - 18:50

The New Researcher Network

Show and Tell Event – for new and early career researchers and PhD Students only.

Lowther Meeting Room, Level -1

Join us for a lively discussion where our guests will delve into their professions.

Full information and booking here.

08:00

Registration and Refreshments

09:00 - 09:05

Winner of The DDL2024 Emerging Scientist Award Announced

The winner of this award will be announced live on stage and will present their research.

This award recognises significant scientific accomplishment or innovation during the early stages of an individual’s career in inhalation science.

09:05 - 09:35

The DDL2024 Emerging Scientist

Winner’s Presentation

09:35 - 09:40

SESSION 4 – ADVANCES IN NASAL DRUG DELIVERY

09:40 - 10:05

Current Opportunities in Nasal Drug Delivery

Julie Suman, Aptar Pharma

10:05 - 10:20

Spray-Dried Powder Nasal Vaccines: A Novel Strategy for Combating Global Infectious Diseases

Hui Wang, University of Alberta

10:20 - 10:35

Investigation of the Impact of Particle Size and Patient Factors on the Nasal Deposition of a Life-Saving Epinephrine Product (Nasdepi®)

Brian Taubenheim, Belhaven Biopharma Inc. 

10:35 - 11:40

Refreshment Break

Explore the exhibition stands, view the posters, and network with delegates.

11:40 - 11:45

SESSION 4 CONTINUED – ADVANCES IN NASAL DRUG DELIVERY

11:45 - 12:10

Utilization of Non-Clinical Models in Intranasal Drug Development

Philip Kuehl, Lovelace Biomedical Research Institute

12:10 - 12:25

Computational Approach for Estimation of Formulation-dependent Fluid Dynamics in a Nasal Delivery Device

Hessam Rasooli Nia, University of Hertfordshire

12:25 - 12:40

Evaluating the Impact on Spray Performance of Tuning Various Configuration Aspects of a User Independent Unit Dose Nasal Delivery Device

Sabrina Falloon, Bespak

12:40 - 12:55

Evaluating Nasal Mucus Simulant Application to the Aeronose® Nasal Cast for Deposition Studies

Lucy Goodacre, King’s College London

12:55 - 14:30

Networking Lunch in the Exhibition Hall and Poster Hall

Network with delegates, visit the exhibition stands and view the conference posters.

Lunch is served in the exhibition hall and poster hall.

14:30 - 14:35

SESSION 5: THE PAT BURNELL YOUNG INVESTIGATOR AWARD

Finalists present their work and are judged by the DDL Organising Committee

The winner of the competition will be announced at the Awards Ceremony on Thursday evening

This award recognises the vision of Pat Burnell and has been designed to encourage junior researchers from either academia or industry to present their work at the DDL Conference.

14:35 - 14:50

Optimised Lamotrigine-Loaded Nanostructured Lipid Carriers for Nose-to-Brain Delivery Reduce Seizure Time in an Epilepsy Model

Niklas Baltz, Kiel University

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14:50 - 15:05

Lactobacilli inhalation powder for the reduction of lung inflammation in non-CF bronchiectasis disease

Stefania Glieca, University of Parma

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15:05 - 15:20

In vitro-In vivo Correlations (IVIVC) of Amorphous Solid Dispersions for Nasal Delivery

Patricia Henriques, Hovione 

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15:20 - 15:35

Customised carrier geometries for inhalation – from in-silico experiments to 3D-printed particles

Melvin Wostry, Kiel University

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15:35 - 15:50

Pharmacokinetic evaluation of controlled release dry powders for inhalation based on budesonide in healthy rats.

Le Van Bui, Université Libre de Bruxelles

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15:50 - 16:05

Assessing low dose aerosolised toxins using the Advanced Integrated Respiratory Model

Patrick He, Woolcock Institute of Medical Research

16:00

Lecture Programme Ends

Exhibition Hall Closes

16:00 - 17:00

Available in the Cromdale Hall (EICC): Afternoon Tea

Following the lectures, there will be light refreshments available for delegates not retuning to their hotels, ahead of the Gala Dinner.

16:00 - 17:00

Gala Dinner Dress Code:

We invite you to dress in festive attire or come as you are, for the dinner and live entertainment.

17:00 - 18:15

Drinks and Canapes will be served in the Poster Hall

Coaches will take delegates from the Conference Centre to the Gala Dinner Venue, at the National Museum of Scotland.

Enjoy the networking drinks reception, whilst we assist you to the coaches.

18:00 - late

DDL Conference 35th Anniversary Gala Dinner

Celebrate with us at the National Museum of Scotland!

Enjoy a fantastic evening of food, drink, live entertainment and the DDL2024 Awards Ceremony in this spectacular venue.

 

Gala Dinner sponsored by:

 

 

 

 

0800

Registration and Refreshments

09:30 - 09:35

SESSION 6 – DEVELOPING INHALATION TECHNOLOGY – LESSONS LEARNT AND CURRENT INNOVATIONS

09:35 - 10:00

Lessons from aerosol science

Rachael Miles & Jonathan Reid, University of Bristol

10:00 - 10:15

Controlling Droplet Size and Spray Duration in Soft Mist Inhalers

Ben De Clercq, Invox Respiratory Innovation Centre

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10:15 - 10:30

Multi-sensory stimulation and reinforcement increases inhalation duration, improves inhaler technique scores and technique retention in pMDI users

Clare Murray, University of Manchester

10:30 - 11:30

Refreshment Break

Explore the exhibition stands, view the conference posters and network with delegates

11:30 - 11:35

SESSION 6 CONTINUED – DEVELOPING INHALATION TECHNOLOGY – LESSONS LEARNT AND CURRENT INNOVATIONS

11:35 - 12:00

Using Spray Drying to Engineer Particles for Inhaled Delivery: Opportunities and Challenges

Richard Johnson, Upperton

12:00 - 12:15

Fast screening of fine particle dose for a Dry Powder Inhaler and a pressurized Metered Dose Inhaler using the Refined-Fast Screening Impactor

Patrik Andersson, AstraZeneca

12:15 - 12:30

Characterizing Deposition Inside an Optically Accessible Dry Powder Inhaler Using Optical Coherence Tomography

Taye Tolu Mekonnen, University of Sydney

12:30

Conference Close

01

Development of an Image Analysis Algorithm to Evaluate Dissolution of Respirable Particles

Nishant Shah, University of Michigan

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02

Enhancing the Therapeutic Efficacy of Nitrofurantoin through Spray Drying: Promoting Extracellular Matrix Protein Deposition in Human Lung Fibroblasts for Emphysema Treatment

Mathew Leslie, Woolcock Institute of Medical Research

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03

Co-variation between mechanical properties and dispersion performance of binary adhesive mixtures of budesonide and lactose

Anna Simonsson, Uppsala University

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04

A Breath of Fresh Hope: Metformin Dry Powder Inhalation for Idiopathic Pulmonary Fibrosis Therapy

Xiujie Liu, The University of Nottingham Ningbo China

 

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05

Exploring Formulation and Spray Drying Operational Parameters for Targeted Upper Airway Delivery

Danni Suhaidi, Deakin University

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06

Using Particle Engineering to Shift Lung Deposition Between the Tracheobronchial and Alveolar Regions: An In Vitro Exploration

Scott Tavernini, University of Alberta

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07

Surface Energy in Dry Powders for Inhalation – a myth or reality?

Zeredescht Majid, University of Kiel

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08

Investigation of the use of resonant acoustic mixing to produce dry powder blends for lung delivery

Cristina Rey Blanes, Chiesi 

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09

Scale-Up of a Spray Dried Formulation for Nasal Drug Delivery

Shailesh Mistry, Upperton Pharma Solutions

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10

Development of a Generalized Method for Quantification of Diverse Types of Amorphous Lactose

Timo Roelofs, DFE Pharma

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11

Nintedanib dry powder inhalers alleviate pulmonary fibrosis induced by bleomycin

Tingting Shi, Western University (University of Western Ontario)

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12

Characterisation of powder microstructure inside blisters using 3D X-ray Imaging

Parmesh Gajjar, InformiX Pharma Limited 

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13

High-dose and Respiratory Variability Tolerance Sivelestat Sodium Nanocrystal-Based Dry Powder Inhalation for the Treatment of Acute Lung Injury

Xuejuan Zhang, College of Pharmacy, Jinan University

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14

On the Influence of Patient-Specific Airways on In-Silico Assessment of Drug Delivery in COPD Patients

Hosein Sadafi, Fluidda N.V.

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15

Ex Vivo Isolated Perfused Rat Lung: A Valuable Tool for assessing the Pulmonary Absorption of Inhaled Drugs

Virginia Patterlini, University of Parma

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16

POSTER WITHDRAWN

17

Kaempferol can increase aerosolization and decrease the cytotoxicity of inhaled cannabidiol

Komal Komal, School of Pharmacy/ University of Otago

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18

Generation of a Control Treatment Database for Reconstructed Airway Epithelial Models – Utility for Generating NAMs

Kamil Czuchrowski, Charles River Laboratories / Heriot Watt University

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19

Factors Influencing Nucleic Acid-Lipid Nanoparticle Stability during Nebulization

Alan Watts, Catalent

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20

Modelling Aerosol Delivery Through the Nostrils of a Horse

Herbert Wachtel, Boehringer Ingelheim Pharma GmbH & Co. KG

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21

Development and evaluation of nebulised oligonucleotide formulations for the treatment of chronic obstructive pulmonary disease

Hui Xin Ong (YY), Ab-Initio Pharma

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22

Complexity when studying nebulized antiviral drug delivery: is ‘simple’ methodology still the answer?

Snezana Radivojev, G.ST Antivirals GmbH

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23

Characterization of a differentiated in vitro porcine epithelial airway model for inhaled drug delivery and mucociliary clearance studies

Janik Martin, University of Applied Sciences Biberach

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24

Cláudia Viegas, Universidade do Algarve

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25

High Nasal Deposition and Controlled Dissolution of Spray Freeze Dried Melatonin Powders

Annika Rautenberg, University of Bonn

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26

Filling Solutions for Engineered Dry Powder Formulations

Jasdip Koner, Aston Particle Technologies

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27

Semaglutide powder for inhalation, pre-formulation and in vitro characterization

Eride Quarta, University of Parma

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28

Co-crystals of Itraconazole and Succinic acid for Inhalation Therapy of Fungal Lung Infections

Hilke Lösing, Kiel University

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29

Enhancing Pulmonary Drug Delivery: A Study on Mixed Particle Formulations

Michael Chow, UCL School of Pharmacy

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30

Quantification of damping of the mixing force in high shear mixing of adhesive mixtures

Kyrre Thalberg, Lund University, Process and Life Science Dept, Food and Pharma Division

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31

Does the filling process with SAK-1 have an influence on the aerodynamic performance?

Angelika Jüptner, Kiel University

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32

Inhalable ceftazidime dry powders for the treatment of Pseudomonas aeruginosa infections in non-cystic fibrosis brochiectasis

Marianna Boraschi, University of Parma

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33

Investigation on API surface energy and morphology for DPI product performance

Vaishnavi Kapileshwari, M2M Pharmaceuticals Ltd.

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34

Effect of valve holding chamber on the dynamics of aerosols: Time resolved velocimetry study

Brenda Hervieu, OptimHal ProtecSom

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35

HFO-1234ze(E): a safe and green propellant supporting sustainability transition in metered dose inhalers

Mark Boelens, Honeywell International Inc.

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36

Plasma Treatment of pMDI Canisters Reduces Dispersive and Acidic Surface Energy

Mahmoud Ahmed, University of Bath

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37

An assessment of Ostwald Ripening potential of Fluticasone Propionate and Salmeterol Xinafoate in Zephex® 152a.

Sally Stanford, Koura, an Orbia Business

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38

Evaluating the Environmental Impact of Inhalers: A Comparative Life Cycle Assessment of DPI Technologies

Francesca Buttini, University of Parma

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39

Minimizing carbon footprint through the construction of a pMDI using the sustainable propellant HFO-1234ze(E) in a solution of BDP and ethanol

Caterina Antiga, University of Parma

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40

In Vitro Analysis of pMDI Particle Size Distributions Penetrating the Extrathoracic Airways Using Laser Diffraction under Dry or Humid Conditions

Kineshta Pillay, University of Alberta

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41

A Tale of 3 Propellants: Understanding the In-Vitro Characteristics of a Solution pMDI

Ameet Sule, H&T Presspart

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42

Supporting a Sustainability Switch – A Laboratory Assessment of HFO-1234ze(E)-based Formulation Performance used with a Commonly Referenced Valved Holding Chamber (VHC)

Mark Nagel, Trudell Medical International

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43

Modulation of regional extrathoracic deposition from pMDIs through selection of actuator orifice diameter

Andrew Martin, University of Alberta

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44

AeroFlex: A Compact, Always-attached VHC Platform for Improving Patient Compliance and Enhancing pMDI Drug Delivery

Zahir Jaffer, Aerodel Technology Innovations Private Limited

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45

Spray Pattern Measurements of Current and Low GWP Propellants HFA152a and HFO1234ze(E) pMDIs: effect of actuator specification

Ben Myatt, Kindeva Drug Delivery

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46

A Multi-Physics Theoretical and CFD Approach, To Predict HFA152a pMDI Spray Characteristics, Inside a USP-IP, and Anatomical Throat Geometries

Hossain Chizari, Kindeva Drug Delivery

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47

The Impact of Two-Phase Propellant Flow Slip Velocity on a Pressurised Metered Dose Inhaler (pMDI) Droplet Size Distribution: A Combination of First Principle & Physics Informed Neural Network (PINN) Approaches

Hossain Chizari, Kindeva Drug Delivery

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48

A Method for Exploring the Evaporation of pMDI Propellant Droplets with Microsecond Time Resolution

Dan Hardy, Microsol

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49

Modular Mouthpiece with Inhalation Sensing Function for Breath-Actuated Nebulisers

Habib Nassar, Acu-Flow Limited (t/a Nebu~Flow)

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50

Determination of Automated Actuation Parameters for Rezenopy™ Nasal Spray Drug Product by Comparison of Hand Study Data for Droplet Size Distribution

Jody Hawkes, Kindeva Drug Delivery 

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51

Measuring Breath Profiles Using an Electronic Incentive Spirometer

Lucas Silva, Nanopharm, An Aptar Pharma Company

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52

Evaluation of Impaction Force of a Jet for Targeted Nasal Drug Delivery

Alain Regard, Nemera La Verpillière

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53

Application of Artificial Intelligence Techniques for Estimating Inhalation Flow Profile Using a Novel Digital Module for Dry Powder Inhaler

Ziyi Fan, Western University

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54

Comprehensive in vitro and in silico Aerodynamic Characterization of Extra Fine Dry Powder Inhalers Containing Nanosized Meloxicam

Petra Party, University of Szeged

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55

Comparative Analysis of Tidal Breathing versus Deep Inhalation and Breath Hold Techniques: Implications for Respiratory Health

Mark Nagel, Trudell Medical International

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56

Adaptive Breath-actuated Mesh Nebulisers: Using In Silico Evidence to Demonstrate Optimisation of Lung Deposition

Edgar Hernan Cuevas Brun, HCmed Innovations Co., Ltd.

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57

Formulation Identification Concept for Smart Nebulisers

Kiing Seng Wong, Acu-Flow Limited (t/a NebuFlow)

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58

PALM: Integrated Ultrasonically-Actuated Platform to Deliver Uniform Aerosol Droplets with Tuneable Diameters

Tuncay Alan, Monash University

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59

Comparison of Rapid Screening Particle Size Analysis with Aerodynamic Performance of Soft Mist Aerosolization Devices

Aurelien Martin, University of Hertfordshire

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60

Pre-Filled Syringe Soft Mist Nasal Spray for Improved Intranasal Drug Delivery

Nicolas Buchmann, Resyca BV

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61

The Missing Link: Coupling Next Generation Impactor Studies with an In-Silico Pulmonary Deposition Model

Toria Legh-Land, Microsol Ltd. 

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62

Synthetic Jet-Assisted Drug Delivery in an Advanced Dry Powder Inhaler

Rina Perven, Monash University

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63

Development of an Integrated Face-Upper Airway Model

Jan Olof Svensson, AstraZeneca

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64

Addressing Variations in Volume and Flow Resistance When Testing Dry Powder Inhalers with Full Resolution and Abbreviated Impactors

Clair Brooks, Copley Scientific Ltd

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65

Increasing the lung dose of inhaled suspensions – Comparison between microsuspension and nanosuspension formulations delivered by a breath-actuated mesh nebuliser

Edgar Hernan Cuevas Brun, HCmed Innovations Co., Ltd.

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66

Evaluating Bioequivalence Acceptance Criteria for In Vitro Dissolution Tests from a Clinical Perspective Using Modelling and Simulation

William Ganley, Nanopharm Ltd., an Aptar Pharma Company

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67

A Novel Approach to Optimising the Design Space of a Dry Powder Inhaler Platform

Heather Jameson, Cambridge Healthcare Innovations

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68

Assessing the impact of realistic breathing profiles in aerosol deposition using in-silico methods

Carolina Dantas, Pulmotree Medical GmbH

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69

Investigation of the Relaxation Effect of Fluticasone Furoate Blends within Ellipta® device

Maribel Bógalo, INTO

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70

Comparability of Aerosol Performance of Salbutamol Sulphate Nebuliser Solution Delivered from Resyca® Pulmospray™ and Prefilled Syringe Inhaler (PFSI™)

Lei Mao, Bespak Laboratories

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71

Administration of soft mist inhaler aerosols using high-flow nasal cannula

Wei-Ren Ke, National Taiwan University

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72

Nebulized host-directed antivirals effectively inhibit respiratory viral infections

Sarah Wideman, G.ST Antivirals

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73

Rapid Deposition Analysis of Drug Delivery to the Human Lungs

Hosein Sadafi, Fluidda N.V.

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74

Oropharyngeal Targeting using a Novel Thermally Gelling Liquid Spray

Madalyn Dankocsik, University of New Mexico College of Pharmacy

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75

On the stability of spray freeze-dried microparticles for pulmonary drug delivery

Lorena Pasero, Politecnico di Torino

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76

eFlow Integrated – Aerosol Performance of a Novel Breath-Triggered Nebulizer

Benjamin Heine, PARI Pharma GmbH

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77

Understanding the Critical Influence of Excipients on Stability and Aerosol Performance of Dry Powder Protein Formulations

Kinnari Santosh Arte, Purdue University

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78

Minimizing Aggregates when Nebulizing Antibody Fab Fragments: High Thermostability and High Concentration are Key

Josi Steinke, Fraunhofer ITEM

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79

Inhaled phage depolymerase-antibiotic combination: A novel therapeutic strategy against lung infections

Honglan Wang, School of Pharmacy, The Chinese University of Hong Kong

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80

From Nebulizer to DPI: Investigating the Feasibility of Producing a Dry Powder Formulation of Deoxyribonuclease I without Reformulation

Aoife Cotter, University of Limerick

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81

Dry Powder Antibody Formulations for Inhalation: Finding the Sweet Spot between High Dose and Protein Stability

Patricia Henriques, Hovione

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82

Spray-Dried Locust Bean Gum Microparticles for Immunomodulation of the Lung

Joana Pinto da Silva, Universidade do Algarve

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83

Liquid Formulation Properties as Prerequisite for Inhalable Dry-powder Properties

Russell Eden, AstraZeneca

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84

An in vivo mouse model for exploring the therapeutic potential of platelets-based therapies in acute lung injury

Anna Kelis, King’s College London

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85

Regenerative and Anti-inflammatory Effects of Platelet Extracts and Their Potential for Development as an Inhaled Medicine

Ziru Xu, King’s College London

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86

Inhalable polyclonal immunoglobulin G for the prevention of airway infections

Rebecca Rittersberger, University of Applied Sciences Biberach

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87

Assessment of the novel soft mist Pre-filled Syringe Inhaler (PFSI) device performance after storage at sub 0 conditions

Imco Sibum, Resyca BV

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88

Pulmonary Delivery of Heparin and its Derivatives as Dry Powder Inhalers for Treating Bacterial Pulmonary Infections and COVID-19

Brayan J. Anaya, Complutense University of Madrid

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89

Optimization of CRISPR/Cas9 lipid nanoparticles for enhanced gene editing in lung cancer cells

Simone Carneiro, Ludwig-Maximilians-Universität München

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90

Nebulization of LAH4-L1/siRNA Complexes Prepared by the Microfluidic Method

Cheng MA, The University of Hong Kong

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91

Pulmonary Administration Of The 2’3’cgamp Entrapped In Liposomes Reprogrammes Immunosuppressive Into Antitumoral Macrophages Against Lung Cancer

Pauline Percier, InhaTarget Therapeutics

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92

Development of a Nanocarrier Formulation for Nebulization to Target Antigen-presenting Cells in the Lungs

Abdallah Ladaycia, Inhatarget Therapeutics

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93

Carbohydrate Azithromycin Loaded Microparticles for Targeting Lung Infections

Gracia Molina, Complutense University of Madrid

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94

Biopharmaceutical Assessment of Excipients Used in Inhalation Drug Delivery

Jean-Pierre Frem, Trinity College Dublin

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95

In Vitro Tracheobronchial Deposition and Dissolution Comparisons for Fluticasone Propionate Delivered by Dry Powder and Pressurized Metered-Dose Inhaler

Scott Tavernini, University of Alberta

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96

Alginate-based Bioaerogel Microparticles for Controlled Pulmonary Drug Delivery

Hao-Ying  Li, King’s Collage, London

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97

Design and Evaluation of Lipid Nanoparticles for Messenger RNA Therapy by Repurposing of ‘Lipid-like’ Cationic Amphiphilic Drugs

Aliona Debisschop, University of Ghent

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98

Tuning pMDI Plume Geometry for Low-GWP Formulations via Orifice Length and Exit Cone Manipulation

Daniel Duke, Monash University

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99

Lipid Dynamics: Investigating the Impact of Compositions on RNA-Loaded Lipid Nanoparticles for Pulmonary Delivery

Simone Carneiro, Lipoid GmbH

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100

Fraction below 10 µm in Nasal Products – A Comparative Study of Laser Diffraction and Aerodynamic Assessment

Niklas Baltz, Kiel University

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101

Orally Inhaled Lipid-based Combination Therapy for the Treatment of Osteosarcoma Lung Metastasis

Federica Carnamucio, Virginia Commonwealth University

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102

Spray-dried Procubosome Microparticles System for Targeted Sustained Pulmonary Delivery of Erlotinib: Design Optimization and In-vitro evaluation

Akash Deep, Punjabi University, Patiala (Punjab), India

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103

Development of a thermoresponsive engineered emulsion for nasal drug delivery

Abhishek Rajbanshi, University of Hertfordshire

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104

Nose-to-brain delivery of ionic complexes loaded in self-nano emulsifying drug delivery systems (SNEDDS) for brain disorders

Debanjan Das, University of Strathclyde

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105

Exploring a thermosensitive polymer for nose-to-brain peptide delivery

Tanisha Khan, Macquarie University

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106

Case Study Utilizing the FDA-Proposed Alternative Approaches to Nasal Drug Product Spray Characterization Release Testing

Ruixin Zhou, Kindeva Drug Delivery

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107

Reliability Expectations for Emergency-Use Nasal Products: IPAC-RS Nasal Subteam Considerations

Adam Gibbons, Consultant

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108

Development of Intranasal Gelling Formulations of Naloxone for Opioid Overdose

Amruta Vaidya, King’s College London

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109

In vitro nasal powder deposition studies: Alberta Idealized Nasal Inlet compared to Realistic Nasal Cast

Georgeta Caraua, University of Parma

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110

Breaking New Ground on Nasal Powders Performance Characterisation: Formulation & Device Integration

António Serôdio, Hovione R&D

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111

Development of a High Dose Nasal Dry Powder Inhaler for Delivery of Antiviral Drugs in a Global Viral Pandemic Context

Ben Wade, Crux Product Design Ltd.

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112

Method development for characterisation of formulations in passive dry powder nasal devices using Alberta Idealised Nasal Inlet

Jakob Samsøe, Iconovo AB

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113

Evaluation of Drug Product Stability of a Nasal Unit Dose Spray Dried Epinephrine Powder (Nasdepi®)

Brian Taubenheim, Belhaven Biopharma Inc.

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114

Solubility of Beclomethasone Dipropionate in Metered Dose Inhaler Propellants and Ethanol Cosolvent Mixtures

Patrick He, Woolcock Institute of Medical Research

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115

Soft Mist Inhaler Performance Analysis

Olivia Brittain, University of Nottingham / Kindeva Drug Delivery

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116

Plume Temperature: A Comparison of HFA134a and HFO1234ze MDIs

Daniel Lewis, OZ UK LTD

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117

Use of High-speed Particle Imaging to Delineate between Different Inhalation Powder Blends

Liam Milton-McGurk, Macquarie University

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118

Collection efficiencies of the Fast Screening Impactor and the Next Generation Impactor using monodisperse polystyrene particles: towards understanding fine particle dose discrepancies

Jan Olof Svensson, AstraZeneca

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119

3D TOF-SIMS to assess magnesium stearate and drug coating in adhesive mixtures for inhalation

Kyrre Thalberg, Lund University, Dept of Process and Life Science Engineering

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120

USP <601> and <1604> Give Different APSD Results

Christopher Gruenloh, PPD, part of Thermo Fisher Scientific

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121

A Performance Comparison of Popular Cup Coatings for the Prevention of Particle Bounce in Next Generation Impactors Using Imaging Techniques and HPLC Analysis

Kelsey Cairns, Inhalytic LTD

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122

Continuous Manufacturing of a Liposomal Gemcitabine Formulation for Local Lung Administration in the Treatment of Osteosarcoma Lung Metastases

Victoria Garcia, Virginia Commonwealth University

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123

Further development on testing to develop clinically meaningful assessment of the aerosolization performance and respirable dose of nebulization devices

Lois Slator, University of hertfordshire

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124

The Evaluation of Equivalence of Mometasone Furoate Nasal Sprays via an In-Vitro Pathway using Dissolution, MDRS and Laser Diffraction Techniques

Lily Richards, Intertek

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125

Comparison of Laser Diffraction and Next Generation Impactor Method in Determination of Droplet Size of Nebulizer Suspensions

Aysenur Kekec, World Medicine Ilac Sanayi ve Ticaret Anonim Sirketi

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126

Investigation of Surface Characteristics of Micronized Salbutamol Sulphate Particles Formulated in Different Propellants using Integrated Scanning Electron Microscopy & Atomic Force Microscopy

Antonia Zapata del Bano, Nanopharm Ltd. (an Aptar Pharma company)

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127

Evaluating Permeation and Leachable Characteristics in Metered Dose Inhalers

Patrice Behem, Aptar Pharma

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