Navigating the Spray Drying Process: Impact of Bulking Excipients on Nasal Powder Manufacture and Process Scalability

Type: Poster

Sana Hosseini*, Ian Vann, Ray Claudio, and Paul Shields

Aptar Pharma, 83 Fulton St., Boonton, NJ 07005 USA

* Corresponding author

 

Summary

Spray drying is a widely used platform in the manufacture of inhaled pharmaceutical products, with growing interest in its application for vaccines and biologics intended for intranasal delivery. Recent efforts focus on improving shelf-life stability and expanding the global availability of vaccines for nasal administration. This study seeks to optimize the spray drying process for intranasal formulations, with a particular focus on the role of bulking excipients.