Paper: Dry Powder Inhalation of Glucagon-like Peptide-1 for Management of Type-2 Diabetes Mellitus
Sanket has pursued his Ph. D. in Pharmaceutical Sciences from CSIR-Central Drug Research Institute (CDRI), Lucknow (India). Currently, he works at Zydus Research Centre (ZRC), Ahmedabad (India) in the department of Novel Drug Delivery Systems (NDDS). Sanket obtained his M.S. (Pharm) in Pharmaceutics from National Institute of Pharmaceutical Education and Research (NIPER). Before joining CSIR-CDRI, he was associated with Novartis (Sandoz Private Limited, Mumbai) for a brief period where he worked in Galenicals (F&D) department at Sandoz Development Centre (SDC).
His research is majorly focused on developing inhalation, intra-nasal and injectable dosage forms. His key interests are into areas of pharmaceutical technology including particle engineering, characterization and optimization of formulation, physicochemical and biological evaluation of novel formulations for pulmonary as well as parenteral delivery. Sanket has commendable experience on developing peptide based drug delivery systems for immediate as well as sustained release. His doctoral thesis focuses on developing and evaluating (in vitro and in vivo) dry powder inhalation of an anti-diabetic peptide for management of type 2 diabetes mellitus. He has also worked on inhalable polymeric micro-particulate drug delivery systems for pulmonary tuberculosis and is quite proficient with techniques such as spray-drying, spray-freeze drying and super-critical fluid (SCF) technology for the preparation of inhalable particles. Sanket is acquainted with using Design of Experiments (QbD) for formula and process optimization; he also has experience on developing an in-house inhalation (DPI) device and evaluating its design using computational fluid dynamics. Sanket has published >10 peer reviewed journal articles and 1 book chapter.